SARS-CoV-2 Rapid Antigen Test in Pediatric Population

The SARS-CoV-2 pandemic has been causing public health challenges worldwide, early and quick detection and isolation of positive cases are crucial to help minimize the number of cases and disease impact on the health care system. The reopening of schools around the world has been a great concern because it could enhance SARS-CoV-2 transmission in the community. The number of tests in school populations has been increased in many countries to prevent outbreaks in classrooms. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) has been established as the reference for microbiologic diagnostic of SARS-CoV-2 infection. Nevertheless, conducting RT-qPCR requires equipment and well-trained personnel and is time-consuming. Consequently, there is a crucial demand for alternative techniques such as antigen detection test, which can detect the presence of the virus in a respiratory sample within minutes. The antigen-based evaluated test is fast, easy to use and highly specific. Considering the good values of specificity, negative and positive predictive values and the low prevalence in the pediatric population, the  SARS-CoV-2 Rapid Antigen Detection Test could be used as a frontline test to obtain quick results.

Antigen Test Kit Sensitivity and Specificity